Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.

Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY.
Circ Heart Fail. 2009 Sep;2(5):446-55. doi: 10.1161/CIRCHEARTFAILURE.108.840124. 

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Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z.
Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2096-108. doi: 10.1152/ajpheart.00452.2009. 

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Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in Timp3-deficient heart.

Kassiri Z, Defamie V, Hariri M, Oudit GY, Anthwal S, Dawood F, Liu P, Khokha R.
J Biol Chem. 2009 Oct 23;284(43):29893-904. doi: 10.1074/jbc.M109.028449.

 

TACE is a key regulator of agonist-induced cardiac hypertrophy and fibrosis. ​Editorial

Wang X, Oka T, Chow FL, Cooper SB, Odenbach J, Lopaschuk GD, Kassiri Z, Fernandez-Patron C.
Hypertension. 2009 Sep;54(3):575-82. doi: 10.1161/HYPERTENSIONAHA.108.127670. 

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SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.
Oudit GY, Kassiri Z, Jiang C, Liu PP, Poutanen SM, Penninger JM, Butany J.
Eur J Clin Invest. 2009 July;39(7):618-25. doi: 10.1111/j.1365-2362.2009.02153.x 

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Loss of TIMP3 enhances interstitial nephritis and fibrosis.

Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, Ziou X, Maeda N, Herzenberg AM, Scholey JW.
J Am Soc Nephrol. 2009 Jun;20(6):1223-35. doi: 10.1681/ASN.2008050492.

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Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy.

Wang X, Chow FL, Oka T, Hao L, Lopez-Campistrous A, Kelly S, Cooper S, Odenbach J, Finegan BA, Schulz R, Kassiri Z, Lopaschuk GD, Fernandez-Patron C.
Circulation. 2009 May 12;119(18):2480-9. doi: 10.1161/CIRCULATIONAHA.108.835488.