Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.
Das SK, Wang W, Zhabyeyev P, Basu R, McLean B, Fan D, Parajuli N, DesAulniers J, Patel VB, Hajjar RJ, Dyck JR, Kassiri Z, Oudit GY.
Sci Rep. 2015 Dec 7;5:18132. doi: 10.1038/srep18132.

​

Identification of a Novel Heart-Liver Axis: Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Lipid Metabolism and Inflammation in the Liver.
Hernandez-Anzaldo S, Berry E, Brglez V, Leung D, Yun TJ, Lee JS, Filep JG, Kassiri Z, Cheong C, Lambeau G, Lehner R, Fernandez-Patron C.
J Am Heart Assoc. 2015 Nov 13;4(11). pii: e002553. doi: 10.1161/JAHA.115.002553.

 

Cardiomyocyte A Disintegrin And Metalloproteinase 17 (ADAM17) Is Essential in Post-Myocardial Infarction Repair by Regulating Angiogenesis.
Fan D, Takawale A, Shen M, Wang W, Wang X, Basu R, Oudit GY, Kassiri Z.
Circ Heart Fail. 2015 Sep;8(5):970-9. doi: 10.1161/CIRCHEARTFAILURE.114.002029. 

​

Extracellular matrix communication and turnover in cardiac physiology and pathology.
Takawale A, Sakamuri SS, Kassiri Z.
Compr Physiol. 2015 Apr;5(2):687-719. doi: 10.1002/cphy.c140045. 

​

Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2.
Patel VB, Takawale A, Ramprasath T, Das SK, Basu R, Grant MB, Hall DA, Kassiri Z, Oudit GY.
J Mol Med (Berl). 2015 Sep;93(9):1003-13. doi: 10.1007/s00109-015-1285-z.

​

Matrix metalloproteinase-2 negatively regulates cardiac secreted phospholipase A2 to modulate inflammation and fever.
Berry E, Hernandez-Anzaldo S, Ghomashchi F, Lehner R, Murakami M, Gelb MH, Kassiri Z, Wang X, Fernandez-Patron C.
J Am Heart Assoc. 2015 Mar 27;4(4). pii: e001868. doi: 10.1161/JAHA.115.001868.

​

Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm. ​Editorial 
Shen M, Lee J, Basu R, Sakamuri SS, Wang X, Fan D, Kassiri Z.
Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):888-98. doi: 10.1161/ATVBAHA.114.305115. 

​

Matrix metalloproteinase-2 mediates a mechanism of metabolic cardioprotection consisting of negative regulation of the sterol regulatory element-binding protein-2/3-hydroxy-3-methylglutaryl-CoA reductase pathway in the heart.
Wang X, Berry E, Hernandez-Anzaldo S, Takawale A, Kassiri Z, Fernandez-Patron C.
Hypertension. 2015 Apr;65(4):882-8. doi: 10.1161/HYPERTENSIONAHA.114.04989.

​

PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.
McLean BA, Zhabyeyev P, Patel VB, Basu R, Parajuli N, DesAulniers J, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY.
Cardiovasc Res. 2015 Mar 1;105(3):292-303. doi: 10.1093/cvr/cvv016.