PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease.

Patel VB, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, McLean BA, Basu R, Zhang P, Shah S, Dawson JF, Pyle WG, Hazra M, Kassiri Z, Hazra S, Vanhaesebroeck B, McCulloch CA, Oudit GY.

Nat Commun. 2018 Dec 19;9(1):5390. doi: 10.1038/s41467-018-07812-8.

 

Endothelial and Cardiomyocyte PI3Kβ Divergently Regulate Cardiac Remodeling in Response to Ischemic Injury.

Chen X, Zhabyeyev P, Azad AK, Wang W, Minerath RA, DesAulniers J, Grueter CE, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY.

Cardiovasc Res. 2018 Nov 28. doi: 10.1093/cvr/cvy298.

 

Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts.

Jana S, Zhang H, Lopaschuk G, Freed DH, Sergi C, Paul K, Oudit GY, Kassiri Z. 

Journal of the American Heart Association.2018 Sep; 7(19). doi: 10.1161/JAHA.118.010427.

 

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.

Presa N, Clugston RD, Lingrell S, Kelly SE, Merrill AH Jr, Jana S, Kassiri Z, Gómez-Muñoz A, Vance DE, Jacobs RL, van der Veen JN.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):14-25. doi: 10.1016/j.bbadis.2018.10.010.

 

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm.

Shen M, Hu M, Fedak PW, Oudit GY, Kassiri Z.

Circ Res. 2018 Jun 21. pii: CIRCRESAHA.118.313181. doi: 10.1161/CIRCRESAHA.118.313181.

 

LOXury of Inhibiting Fibrosis in Volume Overload Cardiomyopathy.

Jana S, Kassiri Z.

Am J Physiol Heart Circ Physiol. 2018 Jun 1. doi: 10.1152/ajpheart.00315.2018.

 

TIMP3 deficiency exacerbates iron overload-mediated cardiomyopathy and liver disease.

Zhabyeyev P, Das SK, Basu R, Shen M, Patel VB, Kassiri Z, Oudit GY.

Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H978-H990. doi: 10.1152/ajpheart.00597.2017. 

 

Guidelines for measuring cardiac physiology in mice.

Lindsey ML, Kassiri Z, Virag JAI, de Castro Brás LE, Scherrer-Crosbie M.

Am J Physiol Heart Circ Physiol. 2018 Apr 1;314(4):H733-H752. doi: 10.1152/ajpheart.00339.2017.

 

Disintegrin and metalloproteinases (ADAMs and ADAM-TSs), the emerging family of proteases in heart physiology and pathology.

Chute M, Jana S, Kassiri Z.  

Curr Opin Physiol. 2018 Feb;1:34-45.doi: 10.1016/j.cophys.2017.07.002

 

Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.

Das SK, Zhabyeyev P, Basu R, Patel VB, Dyck JRB, Kassiri Z, Oudit GY.

Biosci Rep. 2018 Jan 10;38(1). pii: BSR20171302. doi: 10.1042/BSR20171302.